Peer-Reviewed Articles

 

Below are a list of peer-reviewed article publications by the Brain Research Group @ Dartmouth on fluorescence guided resection and brain deformation from 2009 - present.


2011

  • Link to Publication
    Valdes PA, Kim A, Leblond F, Conde OM, Harris BT, Paulsen KD, Wilson BC, Roberts DW. Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery. (Journal of Biomedical Optics. 2011 Oct;16(116006)
  • Link to Publication
    Leblond F, Ovanesyan Z, Davis SC, Valdés PA, Kim A, Hartov A, Wilson BC, Pogue BW, Paulsen KD, Roberts DW. Analytic expression of fluorescence ratio detection correlates with depth in multi-spectral sub-surface imaging. (Phys Med Biol. 2011 Nov 7;56(21):6823-37. Epub 2011 Oct 5)
  • Link to Publication
    Belden CJ, Valdes PA, Ran C Pastel DA, Harris BT, Fadul CE, Israel MA, Paulsen KD, Roberts DW. Genetics of glioblasotma: A window into its imaging and histopathologic variability. (Radiographics. 2011 Oct; 31(6): 1717-1740)
  • Link to Publication
    Valdes PA, Kim A, Bratsch M, Niu C, Moses Z, Tosteson TD, Wilson BC, Paulsen KD, Roberts DW, Harris BT. δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathological markers of malignancy in human gliomas: the need for quantitative fluorescence guided resection to identify regions of increasing malignancy. (Neuro-Oncology. 2011 Aug; 13(8): 846-856 )
  • Link to Publication
    Ji S, Fan X, Roberts DW, Paulsen KD. Cortical Surface Strain Estimation Using Stereovision. (Med Image Comput Comput Assit Interv. 2011;14(Pt 1):412-9.)
  • Link to Publication
    Ji S, Ford JC, Greenwald RM, Beckwith JG, Paulsen KD, Flashman LA, McAllister TW. Automated subject specific, hexahedral mesh generation via image registration. (Finite Elements in Analysis and Design. 2011 Oct 1;47(10):1178-1185.)
  • Link to Publication
    Bekelis K, Valdes PA, Erkmen K, Leblond F, Kim A, Wilson BC, Harris BT, Paulsen KD, Roberts DW. Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningniomas. (Neurosurgical Focus. 2011 May;30(5):E8)
  • Link to Publication
    Whitson W, Valdes PA, Harris BT, Paulsen KD, Roberts DW. Confocal microscopy for the histologic fluorescence pattern of a recurrent atypical meningioma. (Neurosurgery. 2011 [Epub Mar 8])
  • Link to Publication
    Valdes PA, Leblond F, Kim A, Harris BT, Wilson BC, Fan X, Tosteson T, Hartov A, Ji S, Paulsen KD, Roberts DW. Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as a surgical biomarker to guide resection procedures. (J Neurosurg. 2011. [Epub Mar 25])
    • Accompanying editorial:
      Editorial: Ikeda D, Chiocca EA. Measuring versus seeing.
      Response: Roberts DW, Valdes PA, Leblond F, Kim A, Harris BT, Wilson BC, Fan X, Tosteson T, Hartov A, Ji S, Paulsen KD. (J Neurosurg. 2011. [Epub Mar 25])
  • Link to Publication
    Ji S, Roberts DW, Hartov A, Paulsen KD.Real-time interpolation for true 3-dimensional ultrasound image volumes.(J Ultrasound Med. 2011 Feb;30(2):243-52.

2010

  • Link to Publication
    Pogue BW, Gibbs-Strauss S, Valdes PA, Samkoe K, Roberts, DW, Paulsen KD. Review of Neurosurgical Fluorescence Imaging Methodologies. (IEEE Journal of Selected Topics in Quantum Electronics. 2010 Jun; 16(3): 493-505). Invited Review
  • Link to Publication
    Chen Y, Ji S, Wu X, An H, Zhu H, Shen D, Lin W.Simulation of Brain Mass Effect with an Arbitrary Lagrangian and Eulerian FEM. (Med Image Comput Comput Assist Interv. 2010 13(Pt 2): 274-281).
  • Link to Publication
    Hartov A, Paulsen K, Ji S, Fontaine K, Furon ML, Borsic A, Roberts D. Adaptive spatial calibration of a 3D ultrasound system. (Med Phys. 2010 May;37(5):2121-30).
  • Link to Publication
    Roberts DW, Valdes PA, Harris BT, Fontaine KM, Hartov A, Fan X, Ji S, Lollis SS, Pogue BW, Leblond F, Tosteson T, Wilson BC, Paulsen KD. Co-registered Fluorescence-Enhanced Tumor Resection of Malignant Glioma: Relationships between ALA-Induced PpIX Fluorescence, MRI Enhancement and Neuropathological Parameters. (J Neurosurg. 2010 Mar;114(3):595-603. Epub 2010 Apr 9)
  • Link to Publication
    Valdes PA, Samkoe K, O’Hara J, Roberts DW, Paulsen DW, Pogue BW. Deferoxamine Iron Chelation Increases δ-aminolevulinic Acid Induced Protoporphyrin IX in Xenograft Glioma Model. (Photochem Photobiol. 2010 Mar/Apr; 86(2): 471-475. [Epub 2009 Dec 7] )
  • Link to Publication
    Leblond F, Davis SC, Valdes PA, Pogue BW. Pre-clinical Whole-Body Fluorescence Imaging: Review of Instruments, Methods, and Applications. (J Photochem Photobiol B. 2010 Jan 21;98(1):77-94. [Epub 2009 Nov 26] ). Review

2009

  • Link to Publication
    Valdes PA, Fan X, Ji S, Harris BT, Paulsen KD, Roberts, DW. Estimation of Brain Deformation for Volumetric Image Updating in Protoporphyrin IX Fluorescence-Guided Resection. (Stereotactic and Functional Neurosurgery, 2009 Nov 12;88(1):1-10. [Epub 2009 Nov 12])
  • Link to Publication
    Ji S, Hartov A, Roberts D, Paulsen K. Data assimilation using a gradient descent method for estimation of intraoperative brain deformation. (Med Image Anal. 2009 Oct;13(5):744-56. Epub 2009 Jul 9).
  • Link to Publication
    Ji S, Roberts DW, Hartov A, Paulsen KD. Brain-skull contact boundary conditions in an inverse computational deformation model. (Med Image Anal. 2009 Aug;13(4):659-72. Epub 2009 Jun 23).
  • Link to Publication
    Liu F, Lollis SS, Ji S, Paulsen KD, Hartov A, Roberts DW. Model-based estimation of ventricular deformation in the cat brain.(Med Image Comput Comput Assist Interv. 2009;12(Pt 2):308-15).
  • Link to Publication
    Ji S, Roberts DW, Hartov A, Paulsen KD. Combining multiple true 3D ultrasound image volumes through re-registration and rasterization. (Med Image Comput Comput Assist Interv. 2009;12(Pt 1):795-802).

 


 

Conferences and Proceedings

 

Below are a list of conferences and proceedings by the Brain Research Group @ Dartmouth on fluorescence guided resection and brain deformation from 2009 - 2011.


2011

  • Link to Conference
    Valdés PA, Leblond F, Kim A, Harris BT, Wilson BC, Paulsen KD, Roberts DW. ALA-induced PpIX spectroscopy for brain tumor image-guided surgery. (2011) SPIE Photonics West. Proceedings of SPIE Vol. 7883, Photonic Therapeutics and Diagnostics VII (SPIE, Bellingham, WA 2011), 78833P
  • Link to Conference
    Kleen JK, Valdés PA, Harris BT, Holmes GL, Paulsen KD, Roberts DW. ALA-induced PpIX fluorescence in epileptogenic tissue. (2011) SPIE Photonics West. Proceedings of SPIE Vol. 7883, Photonic Therapeutics and Diagnostics VII (SPIE, Bellingham, WA 2011), 78833S
  • Link to Conference
    Ji S, Fan X, Roberts SW, Hartov A, Paulsen KD. Optimizing nonrigid registration performance between volumetric true 3D ultrasound images in image-guided neurosurgery. (2011) SPIE Medical Imaging. Medical Imaging 2011: Visualization, Display and Image-Guided Procedures, Proceedings of SPIE, Lake Buena Vista, (Orlando), Florida USA. 2011.
  • Link to Conference
    Fan X, Ji S, Fontaine K, Hartov A, Roberts DW, Paulsen KD. Simulation of Brain Tumor Resection in Image-guided Neurosurgery. (2011) SPIE Medical Imaging. Medical Imaging 2011: Visualization, Display and Image-Guided Procedures, Proceedings of SPIE, Lake Buena Vista, (Orlando), Florida USA. 2011.

2010

  • Link to Conference
    Valdés, P.A., Leblond, F., Kim, A., Fan, X., Wilson, B.C., Harris, B.T., Paulsen, K.D., Roberts, D.W. Sensitive intraoperative in vivo detection of endogenous biomarker fluorescence from gliomas to maximize brain tumor resection. (2010) World Molecular Imaging Conference. Scientific Session 23: Clinical Studies, Presentation Number 0177.
  • Link to Conference
    Leblond, F., Ovanesyan, Z., Davis, S.C., Krishnaswamy, V., Valdes, P.A., Kim, A., Wilson, B.C., Hartov, A., Pogue, B.W., Paulsen, K.D., Roberts, D.W. Towards depth-resolved fluorescence-guided surgery using multi-spectral near-infrared light. (2010) OSA BIOS. Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BTuD97.
  • Link to Conference
    Valdes, P., Leblond, F., Kim, A., Fan, X., Wilson, B.C., Harris, B.T., Paulsen, K.D., Roberts, D.W. Intraoperative delta-aminolevulinic acid-induced protporphyrin IX spectroscopic quanitfication improves clinical margin delineation of intracranial tumors. (2010) OSA BIOS. Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BTuD95.
  • Link to Conference
    Fan, X., Ji, S., Valdes, P., Roberts, D. W., Hartov, A., Paulsen, K. D. Graphical user interfaces for simulation of brain deformation in image-guided neurosurgery. (2010) SPIE Medical Imaging. Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, edited by Kenneth H. Wong, Michael I. Miga, Proceedings of SPIE Vol. 7625 (SPIE, Bellingham, WA 2009) 762535.
  • Link to Conference
    Ji, S., Fan, X., Roberts, D. W., Hartov, A., Paulsen, K. D. An integrated model-based neursurgical guidance system. (2010) SPIE Medical Imaging. Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, edited by Kenneth H. Wong, Michael I. Miga, Proceedings of SPIE Vol. 7625 (SPIE, Bellingham, WA 2009) 762535.
  • Link to Conference
    Ji S, Greenwald R, Beckwith J, Ford J, McAllister. Person Specific FE Head Model vs. 50th Percentile Male: Does One Size Fit All? (2010) National Neurotrauma Symposium, June 14 - 17, 2010. Las Vegas, Neverda.

2009

  • Link to Conference
    Valdes, P., Harris, B. T., Leblond, F., Fontaine, K. M., Ji, S., Pogue, B. W., Hartov, A., Roberts, D. W., Paulsen, K. D. Brain tumor resection guided by fluorescence imaging and MRI image guidance. (2009) SPIE Medical Imaging. Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, edited by Michael I. Miga, Kenneth H. Wong, Proceedings of SPIE Vol. 7261 (SPIE, Bellingham, WA 2009) 726103.
  • Link to Conference
    Leblond, F., Fontaine, K. M., Valdes, P., Ji, S., Pogue, B. W., Hartov, A., Roberts, D. W., Paulsen, K. D. Brain tumor resection guided by fluorescence imaging. (2009) SPIE Medical Imaging. Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVIII, edited by David H. Kessel, Proceedings of SPIE Vol. 7164 (SPIE, Bellingham, WA 2009) 71640M.
  • Link to Conference
    Ji S, Liu F, Fan X, Hartov A, Roberts DW, Paulsen KD. Model-based brain shift compensation in image-guided neurosurgery. (2009) SPIE Medical Imaging. Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, edited by Michael I. Miga, Kenneth H. Wong, Proceedings of SPIE Vol. 7261 (SPIE, Bellingham, WA 2009) 72612E.