Griswold Group: Publications

 

Peer Reviewed

2015

  • NDong C., Toraya-Brown S., Kekalo K., Baker I., Gerngross T.U., Fiering S.N., Griswold K.E. Antibody-mediated targeting of iron oxide nanoparticles to the Folate receptor alpha increases tumor cell association in vitro and in vivo. International Journal of Nanomedicine (2015), 10: 2595—2617 [Link]
  • Osipovitch D.C., Therrien† S., Griswold K.E. Discovery of novel S. aureus autolysins and molecular engineering to enhance bacteriolytic activity. Applied Microbiology and Biotechnology (2015), Epub ahead of print, doi: 10.1007/s00253-015-6443-2 [Pubmed]
  • Salvatǂ R.S., Choiǂ Y., Bishop† A., Bailey-Kellogg C., Griswold K.E.  Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads. Biotechnology & Bioengineering (2015), Epub ahead of print, doi: 10.1002/bit.25554 [Pubmed]
  • Dostalǂ S.M., Fangǂ Y., Guerrette J.C., Scanlon T.C., Griswold K.E.  Genetically Enhanced Lysozyme Evades a Pathogen Derived Inhibitory Protein. ACS Chemical Biology (2015) Epub ahead of print, doi: 10.1021/cb500976y [Pubmed]
  • Osipovitch, D.C. and Griswold, K.E. Fusion with a cell wall binding domain renders autolysin LytM a potent anti-Staphylococcus aureus agent. FEMS Microbiology Letters (2015), 362(2): 1-7 [Pubmed]
  • NDong C., Tate J.A., Kett W.C., Batra† J., Demidenko E., Lewis L.D., Hoopes P.J., Gerngross T.U., Griswold K.E. Tumor cell targeting by iron oxide nanoparticles is dominated by different factors in vitro versus in vivo. PLoS One (2015), 10(2): e0115636 [Pubmed]
  • Salvat R.S., Parker A.S., Choi Y., Bailey-Kellogg C., Griswold K.E.  Mapping the Pareto Optimal Design Space for a Functionally Deimmunized Biotherapeutic Candidate. PLoS Computational Biology (2015), 11(1): e1003988 [Pubmed]

2014

  • Salvat R.S., Parker A.S., Guilliams† A., Choi Y., Bailey-Kellogg C., Griswold K.E.  Computationally Driven Deletion of Broadly Distributed T cell Epitopes in a Biotherapeutic Candidate. Cellular and Molecular Life Sciences (2014), 71(24): 4869-4880 (Pubmed link: [Pubmed]
  • Griswold K.E., Bement J, Tenneback CC, Scanlon TC, Wargo MJ, Leclair LW,.  Bioengineered lysozyme in combination therapies for Pseudomonas aeruginosa lung infections.  Bioengineered (2014), 5(2): 143-147  [Pubmed]
  • Zhao H., Blazanovic† K., Choi Y., Bailey-Kellogg C., Griswold K.E.  Gene and protein sequence optimization for high level production of fully active and aglycosylated lysostaphin in Pichia pastoris. Applied and Environmental Microbiology (2014), 80(9): 2746-2753 [Pubmed]
  • Salvat R, Moise L, Bailey-Kellogg C, Griswold KE (2014) A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes. Journal of visualized experiments : JoVE (85). doi:10.3791/51308 [Pubmed
  • Scanlon T.C., Dostal S.M., Griswold K.E.  A High Throughput Screen for Antibiotic Drug Discovery. Biotechnology & Bioengineering (2014), 111(2): 232-243 [Pubmed]

2013

  • Teneback C.C., Scanlon T.C., Wargo M..J, Bement J.L., Griswold K.E., Leclair L.W.  Bioengineered lysozyme reduces bacterial burden and inflammation in a murine model of mucoid Pseudomonas aeruginosa lung infection.  Antimicrobial Agents and Chemotherapy (2013), 57(11), pp. 5559-5564 [Pubmed]
  • Lamppa J.W., Tanyos S.A., Griswold K.E.  Engineering Escherichia coli for Soluble Expression and Single Step Purification of Active Human Lysozyme.  Journal of Biotechnology (2013), 164, pp. 1-8 [Pubmed]
  • Choi Y., Griswold K.E., Bailey-Kellogg C.  Structure-based Redesign of Proteins for Minimal T cell Epitope Content.  Journal of Computational Chemistry (2013), 34(10), pp. 879-891 [Pubmed]
  • Lamppa J.W. and Griswold K.E.  Alginate Lyase Exhibits Catalysis-Independent Biofilm Dispersion and Antibiotic Synergy.  Antimicrobial Agents and Chemotherapy (2013), 57(1), pp. 137-145 [Pubmed]
  • Parker A.S., Choi Y.J., Griswold K.E., Bailey-Kellogg C. Structure-Guided Deimmunization of Therapeutic Proteins. Journal of Computational Biology (2013), 20(2), pp. 152-165 [Pubmed]

2012

  • Osipovitch D.C., Parker A.S., Makokha C.D., Desrosiers J., Kett W.C., Moise L., Bailey-Kellogg C., Griswold K.E. Design and Analysis of Immune-Evading Enzymes for ADEPT Therapy. Protein Engineering, Design & Selection (2012), 25(10), pp. 613-624 [Pubmed]

2011

  • Parker, A.S., Griswold, K.E., Bailey-Kellogg, C. Optimization of combinatorial mutagenesis. Journal of Computational Biology (2011), 18(11), pp. 1-14 [Pubmed]
  • Parker, A.S., Griswold, K.E., Bailey-Kellogg, C. Optimization of Therapeutic Proteins to Delete T-Cell Epitopes While Maintaining Beneficial Residue Interactions. Journal of Bioinformatics and Computational Biology (2011), 9(2), pp. 207-229 [Pubmed]
  • Lamppa, J.W., Ackerman, M.E., Lai, J.I., Scanlon, T.C., Griswold, K.E. Genetically Engineered Alginate Lyase-PEG Conjugates Exhibit Enhanced Catalytic Function and Reduced Immunoreactivity. PLoS One (2011), 6(2): e17042 [Pubmed]
  • Gill, A., Scanlon, T.C., Osipovitch, D.C., Madden, D.R., Griswold, K.E. Crystal structure of a charge engineered human lysozyme having enhanced bactericidal activity. PLoS One (2011), 6(3): e16788 [Pubmed]

2010

  • Scanlon, T.C., Teneback, C.C., Gill, A., Bement, J.L., Lamppa, J.W., Weiner, J.A., Leclair, L.W., Griswold, K.E. Enhanced antimicrobial activity of engineered human lysozyme. ACS Chemical Biology (2010), 5(9), pp. 809-818. [Pubmed]
  • Parker, A.S., Zheng, W., Griswold, K.E., Bailey-Kellogg, C. Optimization algorithms for functional deimmunization of therapeutic proteins. BMC Bioinformatics (2010), 11(1), 180. [Pubmed]
  • Zheng, W., Griswold, K.E., Bailey-Kellogg, C. Protein fragment swapping: A method for asymmetric, selective site-directed recombination. Journal of Computational Biology (2010), 17(3), pp. 459-475. [Pubmed]
  • Scanlon, T.C., Jewell, H.L., Gray, E.C., Griswold, K.E. The Monoclonal Myth: addenda to Quantifying and resolving multiple vector transformants in S. cerevisiae plasmid libraries. Bioengineered Bugs, (2010), 1(3), pp. 1-4. [Bioengineered Bugs]

2009

  • Scanlon*, T.C., Gray*†, E.C., Griswold, K.E. Quantifying and Resolving Multiple Vector Transformants in S. cerevisiae Plasmid Libraries. BMC Biotechnology (2009), 9(1), 95. [Pubmed]
  • Zheng, W., Griswold, K.E., Bailey-Kellogg, C. Protein fragment swapping: A method for asymmetric, selective site-directed recombination. Proceedings of the 13th Annual International Conference on Research in Computational Molecular Biology (2009) pp. 321-338. [Link]

2006

  • Griswold, K.E., Aiyappan, N.S., Iverson, B.L., Georgiou, G. The Evolution of Catalytic Efficiency and Substrate Promiscuity in Human Theta Class 1-1 Glutathione Transferase. Journal of Molecular Biology (2006), 364(3), 400-10. [Pubmed]

2005

  • Griswold, K.E., Kawarasaki, Y., Ghoneim, N., Benkovic, S.J., Iverson, B.L., Georgiou, G. Evolution of highly active enzymes by homology-independent recombination. Proceedings of the National Academy of Sciences, USA (2005), 102(29), 10082-7. [Pubmed]
  • Levy, M., Griswold, K.E., Ellington, A.D. Direct selection of trans-acting ligase ribozymes by in-vitro compartmentalization. RNA (2005), 11(10):1555-62. [Pubmed]

2003

  • Kawarasaki, Y., Griswold, K.E., Stevenson, J.D., Selzer, T., Benkovic, S.J., Iverson, B.L., Georgiou, G. Enhanced crossover SCRATCHY: construction and high-throughput screening of a combinatorial library containing multiple non-homologous crossovers. Nucleic Acids Research (2003), 31(21), e126/1-e126/8. [Pubmed]
  • Griswold, K.E., Mahmood, N.A., Iverson, B.L., Georgiou, G. Effects of codon usage versus putative 5'-mRNA structure on the expression of Fusarium solani cutinase in the Escherichia coli cytoplasm. Protein Expression and Purification (2003), 27(1), 134-42. [Pubmed]

Methods

  • Griswold, K.E. pH sensing agar plate assays for esterolytic enzyme activity. Methods in Molecular Biology (Totowa, NJ, United States) (2003), 230, 203-11. [Pubmed]

Book Chapters

  • Georgiou, G., Harvey, B.R., Griswold, K.E., Iverson, B.L. (2005). Applications of Flow Cytometry in Protein Engineering. (Chapter 12) In Larry A. Sklar (Ed), Flow Cytometry in Biotechnology. Oxford University Press. [Google Books]