Iron nanoparticles for magnetic hyperthermia

Iron nanoparticles for magnetic hyperthermia are being developed for cancer treatment. An iron oxide coating is used for either localized magnetic hyperthermia or as a thermal trigger for drugs delivered in vesicles. Localized nanoparticles enable magnetic hyperthermia to treat the tumor with minimal damage to surrounding healthy tissue. Optimization of heating mechanisms (maximum heat rise per unit weight of particles) will allow either smaller tumors to be targeted (possibly even metastases) or a smaller concentration of nanoparticles to be used (thereby minimizing toxic effects), or both.

Faculty contact: Ian Baker, P. Jack Hoopes