Photodynamic therapy

Photodynamic therapy (PDT) is a newly emerging therapy for displastic tissues, such as cancer, age-related blindness, pre-malignant transformation or psoriasis. The therapy involves the administration of a photosensitizing agent, together with the application of moderate intensity light to active the molecules to produce local doses of singlet oxygen. Ongoing research topics include, developing improved dosimetry instrumentation and software, fluorescence tomography imaging to sense drug localization, and assaying unique tumor biology and treatment effects in experimental cancers.

Faculty contact: P. Jack Hoopes, Brian W. Pogue, Stephen Chad Kanick